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Chiu, Brian Chih-Hung

One or more keywords matched the following properties of Chiu, Brian Chih-Hung

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overview	Dr. Chiu investigates the causes and outcomes of lymphoma and multiple myeloma in racial/ethnic and geographically diverse populations using integrated modern molecular techniques and epidemiologic approaches. His current main focus areas are: (1) developing novel epigenetics-based biomarkers in circulating cell-free DNA for prognostication and management of cancers, especially multiple myeloma, (2) identifying lifestyle, biological, and treatment factors that influence the survival and outcomes of multiple myeloma patients, and (3) studying lifestyles, environmental exposures, genetics, and epigenetics that are associated with risks of developing non-Hodgkin lymphoma and multiple myeloma. He is also an active researcher in large international consortia, including the International Lymphoma Epidemiology Consortium (InterLymph), International Multiple Myeloma Consortium (now InterLymph-Myeloma Working Group), and the NCI AsiaLymph. Dr. Chiu’s ongoing NIH-funded and other major research projects include: • Epidemiology of Multiple Myeloma Outcomes at UChicago (EMMOC): Dr. Chiu and his colleagues are enrolling patients with multiple myeloma at the UChicago Medical Center to characterize serial epigenetic signatures in circulating cell-free DNA and evaluate integration with quantitative image-based markers for minimally-invasive assessment of response to myeloma treatment. • Study at UChicago for Cancer Epigenetic EpiDemiology (SUCCEED): Dr. Chiu and his team use a sensitive single-base epigenetic profiling technology to characterize epigenetic modifications in cancers for liquid biopsy-based biomarker discovery in cancer detection and monitoring. • UChicago Myeloma Epidemiology Study: In this clinic-based cohort study at the University of Chicago, Dr. Chiu and his team investigate lifestyle, diet, cytogenetics, genetics, and epigenetic modifications, particularly 5-hydroxymethylcytosine, implicated in the racial/ethnic disparities in the development and outcomes of multiple myeloma. • International Lymphoma Epidemiology Consortium (InterLymph) and AsiaLymph: Dr. Chiu is collaborating with a large group of multi-institute international investigators to investigate the role of environmental exposures and genetic factors in the development of lymphoid malignancies. One of the ongoing major multi-institute initiatives is the InterLymph Genome-Wide Association Study of Lymphoid Malignancies and Related Disorders. Dr. Chiu was also the principal investigator of Taiwan Center for the NCI AsiaLymph study to investigate the contribution of environmental, occupational, and genetic factors to lymphoma risk in Eastern Asia.

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overview

Dr. Chiu investigates the causes and outcomes of lymphoma and multiple myeloma in racial/ethnic and geographically diverse populations using integrated modern molecular techniques and epidemiologic approaches. His current main focus areas are: (1) developing novel epigenetics-based biomarkers in circulating cell-free DNA for prognostication and management of cancers, especially multiple myeloma, (2) identifying lifestyle, biological, and treatment factors that influence the survival and outcomes of multiple myeloma patients, and (3) studying lifestyles, environmental exposures, genetics, and epigenetics that are associated with risks of developing non-Hodgkin lymphoma and multiple myeloma. He is also an active researcher in large international consortia, including the International Lymphoma Epidemiology Consortium (InterLymph), International Multiple Myeloma Consortium (now InterLymph-Myeloma Working Group), and the NCI AsiaLymph. Dr. Chiu’s ongoing NIH-funded and other major research projects include: • Epidemiology of Multiple Myeloma Outcomes at UChicago (EMMOC): Dr. Chiu and his colleagues are enrolling patients with multiple myeloma at the UChicago Medical Center to characterize serial epigenetic signatures in circulating cell-free DNA and evaluate integration with quantitative image-based markers for minimally-invasive assessment of response to myeloma treatment. • Study at UChicago for Cancer Epigenetic EpiDemiology (SUCCEED): Dr. Chiu and his team use a sensitive single-base epigenetic profiling technology to characterize epigenetic modifications in cancers for liquid biopsy-based biomarker discovery in cancer detection and monitoring. • UChicago Myeloma Epidemiology Study: In this clinic-based cohort study at the University of Chicago, Dr. Chiu and his team investigate lifestyle, diet, cytogenetics, genetics, and epigenetic modifications, particularly 5-hydroxymethylcytosine, implicated in the racial/ethnic disparities in the development and outcomes of multiple myeloma. • International Lymphoma Epidemiology Consortium (InterLymph) and AsiaLymph: Dr. Chiu is collaborating with a large group of multi-institute international investigators to investigate the role of environmental exposures and genetic factors in the development of lymphoid malignancies. One of the ongoing major multi-institute initiatives is the InterLymph Genome-Wide Association Study of Lymphoid Malignancies and Related Disorders. Dr. Chiu was also the principal investigator of Taiwan Center for the NCI AsiaLymph study to investigate the contribution of environmental, occupational, and genetic factors to lymphoma risk in Eastern Asia.

One or more keywords matched the following items that are connected to Chiu, Brian Chih-Hung

Item Type	Name
Concept	Adrenal Gland Neoplasms
Concept	Australia
Concept	Autophagy
Concept	Algorithms
Concept	Biotransformation
Concept	Aging
Concept	Alleles
Concept	Blood Proteins
Concept	Antibody Formation
Concept	Asia
Concept	Energy Intake
Concept	Biological Availability
Concept	Body Height
Concept	China
Concept	Blood Glucose
Concept	Body Weight
Concept	Chromosomes, Human, Pair 3
Concept	Chromosomes, Human, Pair 14
Concept	Edible Grain
Concept	Chromosome Deletion
Concept	Chromosomes, Human, 13-15
Concept	C-Reactive Protein
Concept	Glutathione Transferase
Concept	Chromosomes, Human, 16-18
Concept	Diet
Concept	Cytotoxicity, Immunologic
Concept	Europe
Concept	Gastroenteritis
Concept	Gene Frequency
Concept	Graft Survival
Concept	Dietary Proteins
Concept	Connecticut
Concept	Disease Susceptibility
Concept	Eggs
Concept	Glioma
Concept	Gases
Concept	Neoplasms, Radiation-Induced
Concept	Graft Rejection
Concept	Obesity
Concept	Insulin-Like Growth Factor I
Concept	Immunity, Cellular
Concept	Fruit
Concept	Germ Cells
Concept	Meat Products
Concept	Membrane Glycoproteins
Concept	Meat
Concept	Monoclonal Gammopathy of Undetermined Significance
Concept	Minnesota
Concept	Illinois
Concept	Molecular Weight
Concept	Glycosaminoglycans
Concept	Mutation
Concept	Kansas
Concept	Major Histocompatibility Complex
Concept	Selection, Genetic
Concept	Sex Characteristics
Concept	Polymorphism, Genetic
Concept	Feeding Behavior
Concept	Propylene Glycols
Concept	Proteins
Concept	Haplotypes
Concept	Repressor Proteins
Concept	Residence Characteristics
Concept	Insulin Resistance
Concept	Interferon-gamma
Concept	Seasons
Concept	Risk
Concept	Sensitivity and Specificity
Concept	Hong Kong
Concept	Body Mass Index
Concept	Time Factors
Concept	Sunlight
Concept	United States
Concept	Genetic Variation
Concept	Diet, Vegetarian
Concept	Ultraviolet Rays
Concept	Urokinase-Type Plasminogen Activator
Concept	Geriatric Assessment
Concept	Vegetables
Concept	Vitamins
Concept	Up-Regulation
Concept	Exercise
Concept	Milk
Concept	Gene Rearrangement, B-Lymphocyte, Heavy Chain
Concept	Postmenopause
Concept	Motor Activity
Concept	New York
Concept	North America
Concept	Parathyroid Hormone-Related Protein
Concept	Nutritive Value
Concept	Antigen Presentation
Concept	Apoptosis
Concept	Molecular Mimicry
Concept	Micronutrients
Concept	Silicone Gels
Concept	Transplantation Tolerance
Concept	Insulin-Like Growth Factor Binding Proteins
Concept	Insulin-Like Growth Factor Binding Protein 3
Concept	Genetic Association Studies
Concept	Population Groups
Concept	Loss of Heterozygosity
Concept	Gene Expression Profiling
Concept	Polyethylene Glycols
Concept	Animals, Genetically Modified
Concept	Transmembrane Activator and CAML Interactor Protein
Concept	Taiwan
Concept	Host-Pathogen Interactions
Concept	Immunity, Humoral
Concept	Proteolysis
Concept	South Carolina
Concept	Transfection
Concept	Viral Proteins
Concept	Odds Ratio
Concept	Granulocyte Colony-Stimulating Factor
Concept	Ventricular Function, Right
Concept	Metabolic Networks and Pathways
Concept	CD4 Lymphocyte Count
Concept	Cell Lineage
Concept	Ovulation Inhibition
Concept	Genome-Wide Association Study
Concept	Control Groups
Concept	Receptors, Urokinase Plasminogen Activator
Concept	Chromosome Aberrations
Concept	Chromosomes, Human
Concept	Chromosomes, Human, Pair 18
Concept	Dietary Fats
Concept	Dietary Fiber
Concept	Genotype
Concept	Iowa
Concept	Lymphocyte Activation
Concept	Nebraska
Concept	Sex Hormone-Binding Globulin
Concept	Translocation, Genetic
Concept	Transcriptional Activation
Concept	Telomere
Concept	Genetic Predisposition to Disease
Concept	Proto-Oncogene Proteins c-sis
Concept	Polymorphism, Single Nucleotide
Concept	Protein Array Analysis
Concept	Quantitative Trait Loci
Concept	Epigenesis, Genetic
Concept	Reproductive Physiological Phenomena
Concept	Genetic Loci
Academic Article	Diet and risk of non-Hodgkin lymphoma in older women.
Academic Article	Agricultural pesticide use, familial cancer, and risk of non-Hodgkin lymphoma.
Academic Article	An update of the epidemiology of non-Hodgkin's lymphoma.
Academic Article	Cigarette smoking, familial hematopoietic cancer, hair dye use, and risk of t(14;18)-defined subtypes of non-Hodgkin's lymphoma.
Academic Article	The utility of t(14;18) in understanding risk factors for non-Hodgkin lymphoma.
Academic Article	The challenges of epidemiologic research in non-Hodgkin lymphoma.
Academic Article	Vaccination history and risk of non-Hodgkin lymphoma: a population-based, case-control study.
Academic Article	Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph).
Academic Article	Pesticides, chromosomal aberrations, and non-Hodgkin's lymphoma.
Academic Article	Fruit, vegetables, fibre and micronutrients and risk of US renal cell carcinoma.
Academic Article	Association of NAT and GST polymorphisms with non-Hodgkin's lymphoma: a population-based case-control study.
Academic Article	Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women.
Academic Article	Alcohol consumption, family history of hematolymphoproliferative cancer, and the risk of non-Hodgkin's lymphoma in men.
Academic Article	Agricultural pesticide use and risk of t(14;18)-defined subtypes of non-Hodgkin lymphoma.
Academic Article	Dietary factors and risk of t(14;18)-defined subgroups of non-Hodgkin lymphoma.
Academic Article	Risk of brain glioma not associated with cigarette smoking or use of other tobacco products in Iowa.
Academic Article	Longitudinal associations of age, anthropometric and lifestyle factors with serum total insulin-like growth factor-I and IGF binding protein-3 levels in Black and White men: the CARDIA Male Hormone Study.
Academic Article	Body mass index, abnormal glucose metabolism, and mortality from hematopoietic cancer.
Academic Article	Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium.
Academic Article	Toward a global understanding of lymphoma: epidemiologic clues from the second most populous country.
Academic Article	The acceleration in papillary thyroid cancer incidence rates is similar among racial and ethnic groups in the United States.
Academic Article	Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.
Academic Article	Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.
Academic Article	IGF-1, IGFBP-3, and nutritional factors in young black and white men: the CARDIA Male Hormone Study.
Academic Article	Chlamydia pneumoniae infection of endothelial cells induces transcriptional activation of platelet-derived growth factor-B: a potential link to intimal thickening in a rabbit model of atherosclerosis.
Academic Article	Serum IGF-I and C-reactive protein in healthy black and white young men: the CARDIA male hormone study.
Academic Article	Abnormal air collection on plain abdominal X-ray.
Academic Article	Decellularization reduces immunogenicity of sheep pulmonary artery vascular patches.
Academic Article	A genome-wide association study of marginal zone lymphoma shows association to the HLA region.
Academic Article	Silicone gel implant capsules and Chlamydia antigens.
Academic Article	Genotype frequency and F ST analysis of polymorphisms in immunoregulatory genes in Chinese and Caucasian populations.
Academic Article	Rescuing acute rejection of rat cardiac allografts with FTY720.
Academic Article	Patient morbidity and management patterns of community-based primary health care services in Hong Kong.
Academic Article	The impact of race, ethnicity, age and sex on clinical outcome in chronic lymphocytic leukemia: a comprehensive Surveillance, Epidemiology, and End Results analysis in the modern era.
Academic Article	Physical activity, physical function, and the risk of breast cancer in a prospective study among elderly women.
Academic Article	Increase of a urokinase receptor-related low-molecular-weight molecule in colorectal adenocarcinomas.
Academic Article	Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer.
Academic Article	Changes in BMI modulate age-associated changes in sex hormone binding globulin and total testosterone, but not bioavailable testosterone in young adult men: the CARDIA Male Hormone Study.
Academic Article	Surgery combined with controlled-release doxorubicin silk films as a treatment strategy in an orthotopic neuroblastoma mouse model.
Academic Article	From gene expression to serum proteins: biomarker discovery in ankylosing spondylitis.
Academic Article	Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes.
Academic Article	Early Bronchus-Associated Lymphoid Tissue Lymphoma Diagnosed with Immunoglobulin Heavy Chain Molecular Testing.
Academic Article	Multiple myeloma and family history of lymphohaematopoietic cancers: Results from the International Multiple Myeloma Consortium.
Academic Article	A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci.
Academic Article	The effect of an anti-HLA-B27 immune response on CTL recognition of Chlamydia.
Academic Article	Treatment of older patients with diffuse large B-cell lymphoma and mild cognitive impairment or dementia.
Academic Article	Parathyroid hormone-like peptide in normal and neoplastic mesothelial cells.
Academic Article	Myelodysplastic syndrome and acute myeloid leukemia after receipt of granulocyte colony-stimulating factors in older patients with non-Hodgkin lymphoma.
Academic Article	Analysis of hyaluronic acid in the diagnosis of malignant mesothelioma.
Academic Article	Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma.
Academic Article	Mediation analyses of socioeconomic factors determining racial differences in the treatment of diffuse large B-cell lymphoma in a cohort of older adults.
Academic Article	A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry.
Academic Article	Racial Disparities in Intravenous Bisphosphonate Use Among Older Patients With Multiple Myeloma Enrolled in Medicare.
Academic Article	Tumor necrosis factor receptor p55-deficient mice respond to acute Yersinia enterocolitica infection with less apoptosis and more effective host resistance.
Academic Article	Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma.
Academic Article	Associations between frailty and cancer-specific mortality among older women with breast cancer.
Academic Article	Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma.
Academic Article	Loss of 5-hydroxymethylcytosine expression is near-universal in B-cell lymphomas with variable mutations in epigenetic regulators.
Academic Article	Investigation of the incidence trend of follicular lymphoma from 2008 to 2017 in Taiwan and the United States using population-based data.
Academic Article	Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.
Academic Article	Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
Academic Article	Geospatial analysis of population-based incidence of multiple myeloma in the United States.
Concept	Diet, Western
Academic Article	Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes.

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